Strengthening The Reporting Of Genetic Association Studies

February 4, 2009 at 11:00 am Leave a comment

Making sense of rapidly evolving evidence on genetic associations is crucial to making genuine advances in human genomics and the eventual integration
of this information in the practice of medicine and public health. However, “assessment of the strengths and weaknesses of this evidence, and hence
the ability to synthesize it, has been limited by inadequate reporting of results,” says an international team of researchers in this week’s PLoS

Julian Little (University of Ottawa, Ontario, Canada) and colleagues outline their recommendations to improve such reporting-their recommendations
are called the STREGA statement (STREGA stands for Strengthening the REporting of Genetic Association Studies). The statement is being published
simultaneously in six other journals: Annals of Internal Medicine, European Journal of Clinical Investigation, European Journal of Epidemiology,
Genetic Epidemiology, Human Genetics, and Journal of Clinical Epidemiology.


“STrengthening the REporting of Genetic Association Studies
(STREGA)-An extension of the STROBE Statement.”

Little J, Higgins JPT, Ioannidis JPA, Moher D, Gagnon F, et al. (2009)

PLoS Med 6(2): e1000022. doi:10.1371/journal.pmed.1000022

Click here to view article online.

About PLoS Medicine

PLoS Medicine is an open access, freely available international medical journal. It publishes original research that enhances our understanding of
human health and disease, together with commentary and analysis of important global health issues. For more information, visit

About the Public Library of Science

The Public Library of Science (PLoS) is a non-profit organization of scientists and physicians committed to making the world’s scientific and medical
literature a freely available public resource.

Public Library of Science



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